Role of IS26 in antibiotic resistance gene recruitment, dissemination and expression

IS26 在抗生素抗性基因招募、传播和表达中的作用

• 批准号: nhmrc : 1032465
• 负责人: Prof Ruth Hall
• 金额: $ 30.53万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-is26-antibiotic-dissemination-expression/110850
• 关键词: Role; IS26; antibiotic; resistance; gene

Antibiotic resistance is increasing, compromising the efficacy of front-line antibiotics. Untreatable infections due to bacteria that are resistant to all available antibiotics are being seen more often. To control the spread of resistance, an understanding of how resistance arises and is spread among bacteria is needed. This requires information about how the genetic elements that mobilize them work. This project will study one of the most important of these elements.

抗生素耐药性正在增加，影响了一线抗生素的疗效。由于对所有可用抗生素具有耐药性的细菌而导致的无法治疗的感染越来越常见。为了控制耐药性的传播，需要了解耐药性如何产生以及在细菌中传播。这就需要了解动员它们的遗传因素是如何工作的。本项目将研究其中最重要的一个要素。