The biogenesis of cytotoxic granules
The biogenesis of cytotoxic granules
批准号:
nhmrc : 1128587
负责人:
A/Pr Ilia Voskoboinik
金额:
$56.33万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 2020-12-31
中文摘要
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英文摘要
Cytotoxic lymphocytes are immune cells responsible for the killing infected or cancerous cells. How cytotoxic lymphocytes mature from a naive inactive to a fully activated state as they encounter infected or malignant cells is poorly understood, and will be investigated in the current proposal. Our results will aid in the development of novel therapies for cancer and other immunological diseases.
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会议论文
Novel therapies to enhance anti-tumour immunity
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批准号:nhmrc : GNT1139626
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项目类别:Project Grants
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资助金额:$79.76万
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财政年份:2018
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负责人:A/Pr Ilia Voskoboinik
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依托单位:
Novel therapies to enhance anti-tumour immunity
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批准号:nhmrc : 1139626
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项目类别:Project Grants
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资助金额:$53.93万
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财政年份:2018
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负责人:A/Pr Ilia Voskoboinik
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依托单位:
The biogenesis of cytotoxic granules
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批准号:nhmrc : GNT1128587
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项目类别:Project Grants
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资助金额:$82.46万
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财政年份:2017
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负责人:A/Pr Ilia Voskoboinik
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依托单位:
Structural studies on the immune effector perforin: developing mechanism-based inhibitors
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批准号:nhmrc : 1100478
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项目类别:Project Grants
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资助金额:$76.72万
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财政年份:2016
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负责人:A/Pr Ilia Voskoboinik
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依托单位:
Structural studies on the immune effector perforin: developing mechanism-based inhibitors
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批准号:nhmrc : GNT1100478
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项目类别:Project Grants
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资助金额:$111.66万
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财政年份:2016
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负责人:A/Pr Ilia Voskoboinik
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依托单位:
How the immune system controls viral infections and cancer
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批准号:nhmrc : GNT1059126
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项目类别:Research Fellowships
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资助金额:$60.14万
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财政年份:2014
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负责人:A/Pr Ilia Voskoboinik
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依托单位:
Perforinopathy: Immune-disease due to defective perforin function
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批准号:nhmrc : 1062706
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项目类别:Project Grants
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资助金额:$44.78万
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财政年份:2014
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负责人:A/Pr Ilia Voskoboinik
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依托单位:
Regulation and mechanisms of cytotoxic lymphocyte function
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批准号:nhmrc : 1059126
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项目类别:Research Fellowships
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资助金额:$42.08万
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财政年份:2014
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负责人:A/Pr Ilia Voskoboinik
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依托单位:
Dissecting a Serial Killer: Investigating the Degranulation Pathways in Cytotoxic Lymphocytes
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批准号:nhmrc : 1062990
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项目类别:Project Grants
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资助金额:$40.31万
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财政年份:2014
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负责人:A/Pr Ilia Voskoboinik
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依托单位:
Uncovering Perforin Secrets
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批准号:nhmrc : 1029295
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项目类别:Project Grants
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资助金额:$41.31万
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财政年份:2012
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负责人:A/Pr Ilia Voskoboinik
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依托单位:
Structural, Biochemical and Biophysical Studies on Perforin
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批准号:nhmrc : 606557
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项目类别:NHMRC Project Grants
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资助金额:$58.46万
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财政年份:2010
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负责人:A/Pr Ilia Voskoboinik
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依托单位:
Regulation of perforin function and implications for disease
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批准号:nhmrc : 628485
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项目类别:Career Development Fellowships
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资助金额:$29.09万
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财政年份:2010
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负责人:A/Pr Ilia Voskoboinik
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依托单位:
Molecular and cellular mechanisms of cytotoxic lymphocyte perforin
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批准号:nhmrc : 566583
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项目类别:NHMRC Project Grants
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资助金额:$27.95万
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财政年份:2009
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负责人:A/Pr Ilia Voskoboinik
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依托单位:
Mechanisms and function of perforin, A key regulator of immune homoeostasis
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批准号:nhmrc : 454787
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项目类别:Career Development Fellowships
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资助金额:$26.52万
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财政年份:2007
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负责人:A/Pr Ilia Voskoboinik
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依托单位:
Mechanism and regulation of perforin function
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批准号:nhmrc : 400041
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项目类别:NHMRC Project Grants
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资助金额:$29.35万
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财政年份:2006
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负责人:A/Pr Ilia Voskoboinik
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依托单位:
国内基金
海外基金
用识别EBV相关淋巴瘤抗原多肽的T细胞受体做转基因免疫治疗
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批准号:81041002
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项目类别:专项基金项目
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资助金额:10.0万元
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批准年份:2010
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负责人:岑溪南
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依托单位:
Endoglin基因修饰肿瘤/DC杂交细胞诱生靶向特异性抗人肺癌CTL疫苗的研究
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批准号:30760248
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项目类别:地区科学基金项目
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资助金额:16.0万元
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批准年份:2007
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负责人:周源
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依托单位: