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The intersection between hedgehog and notch signalling in medulloblastoma.

The intersection between hedgehog and notch signalling in medulloblastoma.
髓母细胞瘤中刺猬信号和缺口信号之间的交叉点。
批准号:
nhmrc : 631650
负责人:
Prof Brandon Wainwright
金额:
$41.38万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-01-01 至 2012-12-31

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中文摘要
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英文摘要
Brain tumours are the second most common malignancy of childhood and the leading cause of cancer related death and disability in children. Medulloblastoma is the most frequent malignant childhood brain tumour, arising in the cerebellum. This application looks at the relationship between two genetic pathways responsible for medulloblastoma which are also drug targets. Understanding this interaction will lead to better treatment options for the disease.
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Identification of genes causing medulloblastoma by transposon mutagenesis.
  • 批准号:
    nhmrc : 1034941
  • 项目类别:
    Project Grants
  • 资助金额:
    $41.47万
  • 财政年份:
    2012
  • 负责人:
    Prof Brandon Wainwright
  • 依托单位:
Molecular genetics of the host response defect in cystic fibrosis
  • 批准号:
    nhmrc : 401724
  • 项目类别:
    NHMRC Project Grants
  • 资助金额:
    $37.65万
  • 财政年份:
    2007
  • 负责人:
    Prof Brandon Wainwright
  • 依托单位:
The role of Patched/Hedgehog signalling in common human cancer.
  • 批准号:
    nhmrc : 301198
  • 项目类别:
    NHMRC Project Grants
  • 资助金额:
    $33.06万
  • 财政年份:
    2004
  • 负责人:
    Prof Brandon Wainwright
  • 依托单位:
Molecular genetics of cystic fibrosis
  • 批准号:
    nhmrc : 252906
  • 项目类别:
    NHMRC Project Grants
  • 资助金额:
    $39.88万
  • 财政年份:
    2003
  • 负责人:
    Prof Brandon Wainwright
  • 依托单位:
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