Identification of genes causing medulloblastoma by transposon mutagenesis.

通过转座子诱变鉴定引起髓母细胞瘤的基因。

• 批准号: nhmrc : 1034941
• 负责人: Prof Brandon Wainwright
• 金额: $ 41.47万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/identification-genes-causing-transposon-mutagenesis/110942
• 关键词: Identification; genes; causing; medulloblastoma; transposon

Brain tumours are the most common cause of cancer-related death in children and the tumour medulloblastoma is the most frequent. There is a need to develop new therapeutic approaches to treating medulloblastoma through the development of new drugs to directly target the tumour. This research has identified new genes that are good candidates as drug targets for treating medulloblastoma.

脑肿瘤是儿童癌症相关死亡的最常见原因，而髓母细胞瘤是最常见的肿瘤。需要通过开发直接靶向肿瘤的新药来开发治疗髓母细胞瘤的新治疗方法。这项研究已经确定了新的基因，这些基因是治疗髓母细胞瘤的药物靶点。