Antibody targeted thrombin-activatable ?-plasminogen fusion proteins and nanocapsules for the treatment of acute thrombosis
Antibody targeted thrombin-activatable ?-plasminogen fusion proteins and nanocapsules for the treatment of acute thrombosis
批准号:
nhmrc : 1028145
负责人:
A/Pr Christoph Hagemeyer
金额:
$35.8万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2015-12-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
The clinical consequences of atherosclerosis such as myocardial infarction and stroke are the major cause of mortality and morbidity in Australia. Clot dissolving agents have been proven to be beneficial in patients with acute myocardial infarction, vein thrombosis, pulmonary embolism, and stroke. However, the currently available drugs have major limitations in efficacy and in safety. The aim of this project is to develop novel drugs that have the potential to improve both significantly.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Smart targeted nanoparticles for diagnosis and therapy
-
批准号:nhmrc : GNT1154270
-
项目类别:Research Fellowships
-
资助金额:$72.42万
-
财政年份:2019
-
负责人:A/Pr Christoph Hagemeyer
-
依托单位:
Degradable nanocapsules for thromboprophylaxis and treatment of acute thrombosis
-
批准号:nhmrc : GNT1138361
-
项目类别:Project Grants
-
资助金额:$115.84万
-
财政年份:2018
-
负责人:A/Pr Christoph Hagemeyer
-
依托单位:
Degradable nanocapsules for thromboprophylaxis and treatment of acute thrombosis
-
批准号:nhmrc : 1138361
-
项目类别:Project Grants
-
资助金额:$78.33万
-
财政年份:2018
-
负责人:A/Pr Christoph Hagemeyer
-
依托单位:
Molecular imaging and therapy of cardiac fibrosis in atrial fibrillation and heart failure
-
批准号:nhmrc : 1120129
-
项目类别:Project Grants
-
资助金额:$68.96万
-
财政年份:2017
-
负责人:A/Pr Christoph Hagemeyer
-
依托单位:
Molecular imaging and therapy of cardiac fibrosis in atrial fibrillation and heart failure
-
批准号:nhmrc : GNT1120129
-
项目类别:Project Grants
-
资助金额:$102.17万
-
财政年份:2017
-
负责人:A/Pr Christoph Hagemeyer
-
依托单位:
Preclinical development of a therapeutic anticancer antibody to c-Met
-
批准号:nhmrc : 1113743
-
项目类别:Development Grants
-
资助金额:$29.04万
-
财政年份:2016
-
负责人:A/Pr Christoph Hagemeyer
-
依托单位:
Delivering nanoparticles to prevent rupture of unstable arterial plaques
-
批准号:nhmrc : 1078118
-
项目类别:Project Grants
-
资助金额:$40.92万
-
财政年份:2015
-
负责人:A/Pr Christoph Hagemeyer
-
依托单位:
Delivering nanoparticles to prevent rupture of unstable arterial plaques
-
批准号:nhmrc : GNT1078118
-
项目类别:Project Grants
-
资助金额:$59.38万
-
财政年份:2015
-
负责人:A/Pr Christoph Hagemeyer
-
依托单位:
Sortase Peptide Technology: Enzymatic Site-specific Bioconjugation to Improve Antibody Drug Conjugate Production and Performance
-
批准号:nhmrc : 1039017
-
项目类别:Development Grants
-
资助金额:$26.81万
-
财政年份:2012
-
负责人:A/Pr Christoph Hagemeyer
-
依托单位:
Novel 18F and 64Cu labelled targeted nanoparticles for molecular positron emission tomography: A means for early and sensitive detection of thrombosis, inflammation and vulnerable, rupture-prone atherosclerotic plaques
-
批准号:nhmrc : 1029249
-
项目类别:Project Grants
-
资助金额:$38.2万
-
财政年份:2012
-
负责人:A/Pr Christoph Hagemeyer
-
依托单位:
Development of Platelet-Targeted Nanoparticles for Magnetic Resonance Imaging towards the Detection of Thrombi/Emboli and Vulnerable Atherosclerotic Plaques
-
批准号:nhmrc : 1017670
-
项目类别:NHMRC Development Grants
-
资助金额:$40.44万
-
财政年份:2011
-
负责人:A/Pr Christoph Hagemeyer
-
依托单位:
Single-chain antibodies for directed stem cell homing and targeting of effector cells in vascular disease
-
批准号:nhmrc : 472667
-
项目类别:NHMRC Project Grants
-
资助金额:$39.79万
-
财政年份:2008
-
负责人:A/Pr Christoph Hagemeyer
-
依托单位:
Novel Single-chain antibody-targeted nanoparticles for diagnosis of vascular diseases
-
批准号:nhmrc : 472668
-
项目类别:Career Development Fellowships
-
资助金额:$25.38万
-
财政年份:2008
-
负责人:A/Pr Christoph Hagemeyer
-
依托单位:
国内基金
海外基金
登录
查看更多内容
慢性炎症诱发骨丢失的机制及外泌体靶向治疗策略研究
-
批准号:82370889
-
项目类别:面上项目
-
资助金额:49.00万元
-
批准年份:2023
-
负责人:傅德皓
-
依托单位:
基于再生运动神经路径优化Agrin作用促进损伤神经靶向投射的功能研究
-
批准号:82371373
-
项目类别:面上项目
-
资助金额:49.00万元
-
批准年份:2023
-
负责人:沃雁
-
依托单位:
小脑浦肯野细胞突触异常在特发性震颤中的作用机制及靶向干预研究
-
批准号:82371248
-
项目类别:面上项目
-
资助金额:47.00万元
-
批准年份:2023
-
负责人:吴逸雯
-
依托单位:
抑制FGF19/FGFR4信号通路促进肺鳞癌细胞焦亡及免疫增效的机制研究
-
批准号:32100565
-
项目类别:青年科学基金项目(C类)
-
资助金额:30.0万元
-
批准年份:2021
-
负责人:李凡
-
依托单位:
黑色素瘤中PPM1D介导的去磷酸化修饰调控NRAS蛋白功能的机制研究
-
批准号:32100579
-
项目类别:青年科学基金项目(C类)
-
资助金额:30.0万元
-
批准年份:2021
-
负责人:尹成骞
-
依托单位:
Tousled like kinase介导青光眼中视网膜神经节细胞死亡的作用和机制
-
批准号:32000518
-
项目类别:青年科学基金项目
-
资助金额:16.0万元
-
批准年份:2020
-
负责人:赵春月
-
依托单位:
SAMMSON-CARF-p53信号轴调控黑色素瘤适应性耐药的机制研究
-
批准号:32000541
-
项目类别:青年科学基金项目
-
资助金额:24.0万元
-
批准年份:2020
-
负责人:韩戍君
-
依托单位:
CDKL3在肾细胞癌中功能与分子机制的研究及小分子抑制剂的合成与表征
-
批准号:31970721
-
项目类别:面上项目
-
资助金额:58.0万元
-
批准年份:2019
-
负责人:盛韧
-
依托单位:
铁氧还蛋白还原酶FDXR促进雌激素受体阳性乳腺癌内分泌治疗耐药的分子机制研究
-
批准号:31970737
-
项目类别:面上项目
-
资助金额:58.0万元
-
批准年份:2019
-
负责人:张静
-
依托单位:
SIRT1调控突变型p53肿瘤细胞死亡的分子机制研究
-
批准号:31970689
-
项目类别:面上项目
-
资助金额:60.0万元
-
批准年份:2019
-
负责人:闵军霞
-
依托单位: