Preclinical development of a therapeutic anticancer antibody to c-Met
Preclinical development of a therapeutic anticancer antibody to c-Met
批准号:
nhmrc : 1113743
负责人:
A/Pr Christoph Hagemeyer
金额:
$29.04万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Development Grants
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 2017-12-31
中文摘要
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英文摘要
Many common cancers cannot be effectively treated. A range of these cancers (e.g. gastric and lung cancer) display the molecule c-Met on their cell surface. c-Met promotes tumour growth; therefore, blocking c-Met is a promising strategy for treating these cancers. However, no antibodies or drugs that target c-Met have been licensed. The therapeutics that are being developed to target c-Met all have considerable limitations. Thus, there is an opportunity to develop a 'best-in-class' therapeutic.
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