Molecular imaging and therapy of cardiac fibrosis in atrial fibrillation and heart failure

心房颤动和心力衰竭中心脏纤维化的分子成像和治疗

• 批准号: nhmrc : 1120129
• 负责人: A/Pr Christoph Hagemeyer
• 金额: $ 68.96万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/molecular-imaging-therapy-heart-failure/1318141
• 关键词: Molecular; imaging; therapy; cardiac; fibrosis

Cardiac fibrosis is a serious medical condition which can lead to an irregular heart beat and heart failure. We will develop novel diagnostic agents which are more sensitive and able to detect fibrosis of the heart at an earlier time point. This would allow timely initiation of therapy. In addition, we will investigate novel targeted anti-fibrotic agents to treat this devastating disease condition more effectively and with less adverse effects.

心脏纤维化是一种严重的疾病，可导致心律失常和心力衰竭。我们将开发新的诊断试剂，更敏感，能够在更早的时间点检测到心脏纤维化。这将允许及时开始治疗。此外，我们将研究新的靶向抗纤维化药物，以更有效地治疗这种毁灭性的疾病，并减少不良反应。