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Development of Platelet-Targeted Nanoparticles for Magnetic Resonance Imaging towards the Detection of Thrombi/Emboli and Vulnerable Atherosclerotic Plaques

Development of Platelet-Targeted Nanoparticles for Magnetic Resonance Imaging towards the Detection of Thrombi/Emboli and Vulnerable Atherosclerotic Plaques
开发用于磁共振成像的血小板靶向纳米颗粒，以检测血栓/栓子和脆弱的动脉粥样硬化斑块
批准号：
nhmrc : 1017670
负责人：
A/Pr Christoph Hagemeyer
金额：
$40.44万
依托单位：
Baker IDI Heart and Diabetes Institute
依托单位国家：
澳大利亚
项目类别：
NHMRC Development Grants
财政年份：
2011
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2011-01-01 至 2013-12-31
来源：
https://researchdata.edu.au/development-platelet-targeted-atherosclerotic-plaques/109890
关键词：
DevelopmentPlateletTargetedNanoparticlesMagnetic

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英文摘要
Heart attack, stroke and pulmonary embolism typically strike without warning and either kill patients or cause devastating disabilities. Currently, we do not have diagnostic methods to identify patients and the blood vessels at risk. We have developed a new innovative MRI nanoparticle directed against activated platelets for the detection of _at risk� blood vessels. The current funding is requested to optimise the manufacture of this targeted MRI nanoparticle and to undertake the animal studies required to enter early stage clinical trials.
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