Degradable nanocapsules for thromboprophylaxis and treatment of acute thrombosis

可降解纳米胶囊用于血栓预防和治疗急性血栓形成

• 批准号: nhmrc : GNT1138361
• 负责人: A/Pr Christoph Hagemeyer
• 金额: $ 115.84万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/degradable-nanocapsules-thromboprophylaxis-acute-thrombosis/1348138
• 关键词: Degradable; nanocapsules; thromboprophylaxis; treatment; acute

The consequences of fat build up in vessels such as heart attacks and brain infarcts are the major cause of death in Australia. Clot busters have been proven to be beneficial for patients with heart attacks, clots in the legs or lungs and brain infarcts. However, the currently available drugs have major limitations in efficacy and in safety. The aim of this project is to develop novel drugs that have the potential to improve both significantly.

在澳大利亚，脂肪在血管中积聚的后果，如心脏病发作和脑梗死，是导致死亡的主要原因。凝块抑制剂已被证明对心脏病发作、腿部或肺部的凝块以及脑梗死患者有益。然而，目前可用的药物在有效性和安全性方面有很大的局限性。该项目的目的是开发有可能显著改善这两种情况的新药。