Biocompatible synthetic conduits to treat vascular disease

用于治疗血管疾病的生物相容性合成导管

• 批准号: nhmrc : 1075357
• 负责人: A/Pr Martin Ng
• 金额: $ 28.13万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Development Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/biocompatible-synthetic-conduits-vascular-disease/455669
• 关键词: Biocompatible; synthetic; conduits; treat; vascular

Clinically available synthetic conduits used in vascular repair and bypass are fundamentally incompatible with the vasculature. They cause inflammation at the site of implantation and increase the risk of blood clots forming. We have developed a unique method of binding bioactive protein layers to the surface of all polymeric materials and have shown a significant improvement in their compatibility. Grafts coated using our technology stand to dramatically improve the treatment of vascular disease.

用于血管修复和旁路的临床可用的合成导管与脉管系统根本不相容。它们会在植入部位引起炎症，并增加血栓形成的风险。我们开发了一种独特的方法，将生物活性蛋白层结合到所有聚合物材料的表面，并显示出其相容性的显着改善。使用我们的技术涂覆的移植物将显着改善血管疾病的治疗。