The Role of Androgens in Cardiovascular Repair and Regeneration

雄激素在心血管修复和再生中的作用

• 批准号: nhmrc : 1011111
• 负责人: A/Pr Martin Ng
• 金额: $ 30.97万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-androgens-cardiovascular-repair-regeneration/109548
• 关键词: Role; Androgens; Cardiovascular; Repair; Regeneration

Increasing evidence indicates that the heart and blood vessels are able to repair themselves in response to disease. Recent evidence suggests that in men, male sex hormones(e.g. testosterone) may play an important role in helping repair blood vessels. As men get older, their testosterone levels get progressively lower - this lead to impairment of vascular repair mechanisms with aging. We will study the effects of androgens on repair and regeneration of the vasculature.

越来越多的证据表明，心脏和血管能够针对疾病进行自我修复。最近的证据表明，对于男性来说，男性性激素（例如睾酮）可能在帮助修复血管方面发挥重要作用。随着男性年龄的增长，他们的睾酮水平逐渐降低——这会导致血管修复机制随着年龄的增长而受损。我们将研究雄激素对脉管系统修复和再生的影响。