Bioengineering Endovascular Prostheses with Proactive Biocompatibility

具有主动生物相容性的生物工程血管内假体

• 批准号: nhmrc : 1033079
• 负责人: A/Pr Martin Ng
• 金额: $ 41.87万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/bioengineering-endovascular-prostheses-proactive-biocompatibility/110881
• 关键词: Bioengineering; Endovascular; Prostheses; Proactive; Biocompatibility

Metallic cardiovascular implants, such as stents, used in the treatment of heart disease are not compatible with blood. They cause inflammation at the site of implantation and increase the risk of blood clots forming. We have developed a unique method of binding bioactive protein layers to the surface of metal alloys, and shown a significant improvement in their compatibility. Stents coated using our technology stand to dramatically improve the treatment of cardiovascular disease.

用于治疗心脏病的金属心血管植入物，如支架，与血液不相容。它们会在植入部位引起炎症，并增加血栓形成的风险。我们开发了一种独特的将生物活性蛋白质层结合到金属合金表面的方法，并显示出它们之间的兼容性有了显著的改善。使用我们的技术覆盖的支架可以极大地提高心血管疾病的治疗水平。