The protective effects of fenofibrate in diabetes-related susceptibility to ischaemia

非诺贝特对糖尿病相关缺血易感性的保护作用

• 批准号: nhmrc : 1066541
• 负责人: A/Pr Martin Ng
• 金额: $ 42.05万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/protective-effects-fenofibrate-susceptibility-ischaemia/455243
• 关键词: protective; effects; fenofibrate; diabetes; related

Blood flow reduction (blockage of arteries) to local tissue is a common problem for diabetic people. Fenofibrate, a cholesterol lowering drug, dramatically reduces the diabetes-related limb amputation and other vascular disorders. We plan to study the mechanism of fenofibrate to facilitate growth of new blood vessels to sites affected by vascular disease. Ultimately, this may result in new treatment for diabetic vascular complications.

局部组织血流量减少（动脉阻塞）是糖尿病患者的常见问题。非诺贝特是一种降低胆固醇的药物，可显着减少与糖尿病相关的截肢和其他血管疾病。我们计划研究非诺贝特促进受血管疾病影响部位新血管生长的机制。最终，这可能会带来糖尿病血管并发症的新治疗方法。