Developing more effective synthetic conduits to treat vascular disease

开发更有效的合成导管来治疗血管疾病

• 批准号: nhmrc : GNT1066174
• 负责人: A/Pr Martin Ng
• 金额: $ 40.27万
• 依托单位: University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/developing-effective-synthetic-vascular-disease/1344904
• 关键词: Developing; more; effective; synthetic; conduits

An arterial substitute with both physical and biological properties that mimic those of the human vasculature has long been the holy grail of vascular tissue engineering. We propose synthetic elastin can form the basis of a durable, clinically effective small diameter vascular graft and fill a significant unmet need for a biocompatible vascular substitute.

一种具有模拟人体血管系统的物理和生物学特性的动脉替代物一直是血管组织工程的圣杯。我们提出合成弹性蛋白可以形成耐用的、临床有效的小直径血管移植物的基础，并填补了对生物相容性血管替代物的显著未满足的需求。