Cell therapy for enteric neuropathies - the essential next steps

肠神经病的细胞疗法——接下来的重要步骤

• 批准号: nhmrc : 1079234
• 负责人: Prof Heather Young
• 金额: $ 44.49万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/cell-therapy-enteric-essential-steps/518646
• 关键词: Cell; therapy; enteric; neuropathies; essential

Gastrointestinal motility disorders caused by damage or diseased neurons in the gut wall ("enteric neuropathies) are some of the most clinically challenging conditions to manage because of a lack of effective treatments. Our recent animal studies suggest that cell-based therapies are a real possibility to treat enteric neuropathies. In this project, we will methodically address the outstanding steps that need to be addressed with the aim of moving enteric cell therapies to the clinic.

由于缺乏有效的治疗方法，由肠壁中的损伤或患病神经元引起的胃肠动力障碍（“肠神经病"）是一些临床上最具挑战性的病症。我们最近的动物研究表明，基于细胞的治疗是一个真实的可能性，以治疗肠神经病变。在这个项目中，我们将有条不紊地解决需要解决的突出步骤，目的是将肠细胞疗法推向临床。