Chemical Biology and Drug Discovery of Cell Death

细胞死亡的化学生物学和药物发现

• 批准号: nhmrc : 1117089
• 负责人: A/Pr Guillaume Lessene
• 金额: $ 48.17万
• 依托单位: The Walter and Eliza Hall Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/chemical-biology-drug-cell-death/946171
• 关键词: Chemical; Biology; Drug; Discovery; Cell

Programmed cell death regulates the fate of cells during development and adult life. Working at the frontier of biology and chemistry, I lead research programs committed to uncovering cell death processes implicated in a wide range of diseases such as cancer, inflammatory diseases and tissue damage. I will develop novel small molecules that will act as powerful tools to increase our understanding of how cell death participates in these conditions and help develop new drugs to treat them.

细胞程序性死亡控制着细胞在发育和成体过程中的命运。我工作在生物和化学的前沿，领导着致力于揭示细胞死亡过程的研究项目，这些过程与癌症、炎症性疾病和组织损伤等一系列疾病有关。我将开发新的小分子，作为强大的工具，增加我们对细胞死亡如何参与这些条件的理解，并帮助开发治疗这些疾病的新药。