Development of small molecules for the treament of colon cancer

开发治疗结肠癌的小分子

• 批准号: nhmrc : 1017059
• 负责人: A/Pr Guillaume Lessene
• 金额: $ 45.63万
• 依托单位: The Walter and Eliza Hall Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Development Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/development-small-molecules-colon-cancer/109823
• 关键词: Development; small; molecules; treament; colon

Colon cancer remains one of the leading causes of cancer related deaths in Australia and in the developed world. Despite improvements in prevention and therapies, there remains a considerable need for efficacious therapeutic options. We have identified a lead compound inhibiting the growth of cancer cells. We will progress this series further toward clinical trials and aim to provide patients with a new orally available molecule with potent activity against colon cancer.

在澳大利亚和发达国家，结肠癌仍然是癌症相关死亡的主要原因之一。尽管在预防和治疗方面有所改进，但仍然需要大量有效的治疗选择。我们已经确定了一种抑制癌细胞生长的先导化合物。我们将进一步推进该系列的临床试验，旨在为患者提供一种新的口服分子，具有有效的抗结肠癌活性。