Targeting viral Bcl-2 proteins for therapy
Targeting viral Bcl-2 proteins for therapy
批准号:
nhmrc : 637336
负责人:
A/Pr Guillaume Lessene
金额:
$20.8万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-01-01 至 2012-12-31
中文摘要
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英文摘要
Failure to correctly regulate cell death leads to a number of diseases, including cancers and auto-immune diseases. Viruses have the ability to hijack the host cell death machinery for their own benefit. Viral infections have been linked to a number of cancers. We aim to target the ability of viruses to hijack the process of cell death to develop new treatments against virus-linked cancers including Burkitt's Lymphoma and Nasopharyngeal Carcinoma.
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会议论文
Chemical Biology and Drug Discovery of Cell Death
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批准号:nhmrc : 1117089
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项目类别:Research Fellowships
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资助金额:$48.17万
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财政年份:2017
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负责人:A/Pr Guillaume Lessene
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依托单位:
Apoptosis and Stem/Progenitor Cells in the Development and Treatment of Cancer
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批准号:nhmrc : 1113133
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项目类别:Program Grants
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资助金额:$1491.14万
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财政年份:2017
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负责人:A/Pr Guillaume Lessene
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依托单位:
Chemical Biology and Drug Discovery of Cell Death
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批准号:nhmrc : GNT1117089
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项目类别:Research Fellowships
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资助金额:$70.64万
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财政年份:2017
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负责人:A/Pr Guillaume Lessene
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依托单位:
Apoptosis and Stem/Progenitor Cells in the Development and Treatment of Cancer
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批准号:nhmrc : GNT1113133
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项目类别:Programs
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资助金额:$2180.96万
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财政年份:2017
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负责人:A/Pr Guillaume Lessene
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依托单位:
Small molecule apoptosis inhibitors to define the Bak activating switch
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批准号:nhmrc : 1083077
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项目类别:Project Grants
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资助金额:$47.59万
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财政年份:2015
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负责人:A/Pr Guillaume Lessene
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依托单位:
Chemical biology investigation of cell death processes: development of molecular probes interfering with necroptosis
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批准号:nhmrc : 1067289
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项目类别:Project Grants
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资助金额:$42.06万
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财政年份:2014
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负责人:A/Pr Guillaume Lessene
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依托单位:
Chemical and structural biology validation of Lamin B1 as a new anti-cancer target
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批准号:nhmrc : 1057805
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项目类别:Project Grants
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资助金额:$42.56万
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财政年份:2014
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负责人:A/Pr Guillaume Lessene
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依托单位:
Understanding the activation of pro-apoptotic Bcl-2 family proteins for the development of modulators of apoptosis
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批准号:nhmrc : 1059331
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项目类别:Project Grants
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资助金额:$41.86万
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财政年份:2014
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负责人:A/Pr Guillaume Lessene
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依托单位:
Development of small molecule modulators of apoptosis
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批准号:nhmrc : 1025138
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项目类别:Project Grants
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资助金额:$41.45万
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财政年份:2012
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负责人:A/Pr Guillaume Lessene
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依托单位:
Development of small molecules for the treament of colon cancer
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批准号:nhmrc : 1017059
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项目类别:Development Grants
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资助金额:$45.63万
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财政年份:2011
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负责人:A/Pr Guillaume Lessene
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依托单位:
Targeting viral Bcl-2 members for therapy
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批准号:nhmrc : GNT0637336
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项目类别:Project Grants
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资助金额:$30.65万
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财政年份:2010
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负责人:A/Pr Guillaume Lessene
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依托单位:
国内基金
海外基金
大豆MYB(v-myb avian myeloblastosis viral oncogene homolog)转录因子基因对大豆异黄酮合成调控的研究
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批准号:31371641
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项目类别:面上项目
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资助金额:15.0万元
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批准年份:2013
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负责人:王庆钰
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依托单位:
植物病毒壳体"智能"纳米载体靶向肿瘤细胞的研究
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批准号:30973685
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项目类别:面上项目
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资助金额:35.0万元
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批准年份:2009
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负责人:曾庆冰
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依托单位:
中国棉铃虫单核衣壳核多角体病毒膜融合蛋白的结构和功能研究
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批准号:30300012
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项目类别:青年科学基金项目
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资助金额:20.0万元
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批准年份:2003
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负责人:龙钢
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依托单位: