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Restoration of the nigrostriatal pathway in the Parkinsonian brain

Restoration of the nigrostriatal pathway in the Parkinsonian brain
帕金森病大脑黑质纹状体通路的恢复
批准号:
nhmrc : 628542
负责人:
A/Pr Clare Parish
金额:
$19.97万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-01-01 至 2012-12-31

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项目成果

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中文摘要
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英文摘要
Many obstacles exist for cell transplantation in Parkinson's disease; namely poor restoration of the host brain circuitry due to incorrect graft placement. This results in incomplete motor function and unwanted side effects. Through iterative studies we endeavor to restore this circuitry by placing grafts in the appropriate location and promoting their survival and growth-integrations. This will require: optimizing the donor tissue and exposure of the graft to growth stimulating factors.
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Advancing stem cell therapy for brain repair
  • 批准号:
    nhmrc : GNT1154744
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $64.92万
  • 财政年份:
    2019
  • 负责人:
    A/Pr Clare Parish
  • 依托单位:
Biomaterials for the direct reprograming of reactive astrocytes into functional neurons
  • 批准号:
    nhmrc : 1144996
  • 项目类别:
    Project Grants
  • 资助金额:
    $42.63万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Clare Parish
  • 依托单位:
Biomaterials for the direct reprograming of reactive astrocytes into functional neurons
  • 批准号:
    nhmrc : GNT1144996
  • 项目类别:
    Project Grants
  • 资助金额:
    $63.05万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Clare Parish
  • 依托单位:
Testing the Prion Hypothesis in Parkinson’s Disease using a Novel In Vivo Model of ?-synuclein Transmission
  • 批准号:
    nhmrc : 1145348
  • 项目类别:
    Project Grants
  • 资助金额:
    $42.09万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Clare Parish
  • 依托单位:
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