Using stem cells and bioengineered scaffolds to promote regeneration following necrotic brain injury

使用干细胞和生物工程支架促进坏死性脑损伤后的再生

• 批准号: nhmrc : 1122974
• 负责人: A/Pr Clare Parish
• 金额: $ 48.54万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/using-stem-cells-brain-injury/947059
• 关键词: Using; stem; cells; bioengineered; scaffolds

A number of injuries, including stroke, result in tissue loss. Consequently promoting repair will require restoration of tissue structure, replacement cells and a supportive environment to promote integration of these new cells. This study will engineer and develop novel scaffolds that can replace tissue whilst additionally providing physical and chemical support for newly implanted stem cells. This work will be conducted in an animal model of stroke.

许多伤害，包括中风，都会导致组织损失。因此，促进修复需要恢复组织结构、替代细胞和支持性环境来促进这些新细胞的整合。这项研究将设计和开发可以替代组织的新型支架，同时为新植入的干细胞提供物理和化学支持。这项工作将在中风动物模型中进行。