Biomaterials for the direct reprograming of reactive astrocytes into functional neurons
Biomaterials for the direct reprograming of reactive astrocytes into functional neurons
批准号:
nhmrc : GNT1144996
负责人:
A/Pr Clare Parish
金额:
$63.05万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 --
中文摘要
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英文摘要
We will employ peptide inspired hydrogel nanoscaffolds that can be injected into a brain lesion as a single injection to provide chemical and physical support for the surrounding cells. We will utilize various modifications to these materials to reprogram inflammatory cells into neurons, whilst also promoting the survival, maintenance and growth of existing neurons to encourage repair.
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