Connecting the dots: Image analysis for single molecule localisation microscopy
Connecting the dots: Image analysis for single molecule localisation microscopy
批准号:
LP140100967
负责人:
Prof Katharina Gaus
金额:
$27.23万
依托单位国家:
澳大利亚
项目类别:
Linkage Projects
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-09-25 至 2019-12-31
中文摘要
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英文摘要
It is now possible to record the positions of single fluorescent molecules in intact cells to build up an image literally molecule by molecule. But how to ‘connect the dots’ and extract structural information from molecular coordinates is yet to be worked out. The project aims to do exactly that, and write and implement novel analysis routines to quantify a diverse range of biological structures such as protein complexes, membrane morphologies, filamentous cytoskeletal networks, vesicles and viruses. The project is a collaboration between a cell biologist (Professor Gaus) who is a leader in single molecule localisation microscopy, an expert in fluorescence image analysis (Dr Nicovich) and an industry partner (Dr Lucas) who has a sophisticated software platform.
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Molecular mechanisms in cholesterol export.
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依托单位:
国内基金
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