Single molecule imaging laboratory

单分子成像实验室：本项目的目标是建立单分子成像实验室，以缩小结构成像和细胞成像之间的差距。利用ARC高级分子成像卓越中心的专业知识，该项目的目的是设计，建造和应用三种显微镜，超越目前单分子定位显微镜的商业解决方案，如光活化定位显微镜（PALM）和随机光学重建显微镜（STORM），并执行单分子成像：该设备将具有快速的采集速率，以监测高度动态的分子事件，并提高精确度，以小于或等于1纳米的分辨率对完整细胞中的分子和复合物进行成像。目前世界上没有类似的成像设施。

Single molecule imaging laboratory: The goal of the project is to establish a single molecule imaging laboratory to close the gap between structural imaging and cellular imaging. Utilising the expertise of the ARC Centre of Excellence in Advanced Molecular Imaging, the aim of the project is to design, build and apply three microscopes that go beyond the current commercial solutions for single molecule localisation microscopy such as Photo-Activation Localisation Microscopy (PALM) and Stochastic Optical Reconstruction Microscopy (STORM) and perform single molecule imaging: deep inside cells and tissue.The facility will have a fast acquisition rate to monitor highly dynamic molecular events, and improved precision to image molecules and complexes in intact cells with less than or equal to one nanometre resolution. There is currently no comparable imaging facility in the world.