Suppression of Immune Toll-like receptor (TLR) signaling by Hepatitis B e Antigen (HBeAg)
Suppression of Immune Toll-like receptor (TLR) signaling by Hepatitis B e Antigen (HBeAg)
批准号:
nhmrc : 491017
负责人:
A/Pr Ashley Mansell
金额:
$36.16万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2008
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2008-01-01 至 2010-12-31
中文摘要
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英文摘要
Hepatitis B virus (HBV) infection is a major world-wide health problem, which the current treatment strategies are not ideal. Therefore understanding how HBV inteacts with the immune system is of critical importance to developing intervention strategies to promote better health outcomes. This grant will develop our novel findings that a protein produced by HBV 'blinds' the host immune system by producing a protein that blocks the innate immune response to allow HBV to replicate unchallenged.
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会议论文
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Targeting renal and vascular inflammation in hypertension
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依托单位:
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依托单位:
Toll-like receptor and MyD88 signalling in the testis
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财政年份:2011
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依托单位:
H1N1 Development of a signature for early responses to influenza strains that determine -correlate with severity of infe
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财政年份:2009
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依托单位:
Cross-talk between cytokine and pathogen recognition receptor networks in the pathogenesis of gastric cancer
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批准号:nhmrc : 490956
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依托单位:
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依托单位:
The role of Mal in Toll-like receptor signal transduction of the pro-inflammatory response.
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依托单位:
海外基金