Targeting renal and vascular inflammation in hypertension
Targeting renal and vascular inflammation in hypertension
批准号:
nhmrc : 1062721
负责人:
A/Pr Ashley Mansell
金额:
$52.12万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2016-12-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Inflammation is a hallmark of high blood pressure (A.K.A. hypertension) and underlies clinical complications of the condition such as kidney failure and blood vessel disease. This project will investigate whether a recently described signaling complex termed the 'inflammasome' is a trigger of inflammation in hypertension in the hope of identifying it as a target for new drugs that are more effective in the treatment of hypertension and its complications.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
INFLAMMASOMES AND INTERLEUKIN-18 SIGNALLING: NOVEL BIOMARKERS AND THERAPEUTIC TARGETS FOR KIDNEY DISEASE
-
批准号:nhmrc : GNT1143674
-
项目类别:Project Grants
-
资助金额:$100.33万
-
财政年份:2018
-
负责人:A/Pr Ashley Mansell
-
依托单位:
INFLAMMASOMES AND INTERLEUKIN-18 SIGNALLING: NOVEL BIOMARKERS AND THERAPEUTIC TARGETS FOR KIDNEY DISEASE
-
批准号:nhmrc : 1143674
-
项目类别:Project Grants
-
资助金额:$67.84万
-
财政年份:2018
-
负责人:A/Pr Ashley Mansell
-
依托单位:
Regulation of immune responses in the adult testis and male reproductive health
-
批准号:nhmrc : GNT1125149
-
项目类别:Project Grants
-
资助金额:$63.79万
-
财政年份:2017
-
负责人:A/Pr Ashley Mansell
-
依托单位:
Regulation of immune responses in the adult testis and male reproductive health
-
批准号:nhmrc : 1125149
-
项目类别:Project Grants
-
资助金额:$43.53万
-
财政年份:2017
-
负责人:A/Pr Ashley Mansell
-
依托单位:
Characterization and inhibition of higher-order assembly signalling in Toll-like receptor pathways
-
批准号:nhmrc : GNT1107804
-
项目类别:Project Grants
-
资助金额:$71.2万
-
财政年份:2016
-
负责人:A/Pr Ashley Mansell
-
依托单位:
Characterization and inhibition of higher-order assembly signalling in Toll-like receptor pathways
-
批准号:nhmrc : 1107804
-
项目类别:Project Grants
-
资助金额:$48.83万
-
财政年份:2016
-
负责人:A/Pr Ashley Mansell
-
依托单位:
PB1-F2 is critical to Influenza A virus pathogenicity through activation of the inflammasome
-
批准号:nhmrc : 1079924
-
项目类别:Project Grants
-
资助金额:$44.27万
-
财政年份:2015
-
负责人:A/Pr Ashley Mansell
-
依托单位:
PB1-F2 is critical to Influenza A virus pathogenicity through activation of the inflammasome
-
批准号:nhmrc : GNT1079924
-
项目类别:Project Grants
-
资助金额:$64.31万
-
财政年份:2015
-
负责人:A/Pr Ashley Mansell
-
依托单位:
Defining the role of the novel gene MUL1 in antiviral innate immunity
-
批准号:nhmrc : 1062977
-
项目类别:Project Grants
-
资助金额:$34.11万
-
财政年份:2014
-
负责人:A/Pr Ashley Mansell
-
依托单位:
Molecular and structural basis of signalling by TIR domain-containing adaptors in TLR pathways
-
批准号:nhmrc : 1003326
-
项目类别:Project Grants
-
资助金额:$44.44万
-
财政年份:2011
-
负责人:A/Pr Ashley Mansell
-
依托单位:
Toll-like receptor and MyD88 signalling in the testis
-
批准号:nhmrc : 1011115
-
项目类别:NHMRC Project Grants
-
资助金额:$33.23万
-
财政年份:2011
-
负责人:A/Pr Ashley Mansell
-
依托单位:
H1N1 Development of a signature for early responses to influenza strains that determine -correlate with severity of infe
-
批准号:nhmrc : 606976
-
项目类别:NHMRC Strategic Awards
-
资助金额:$21.29万
-
财政年份:2009
-
负责人:A/Pr Ashley Mansell
-
依托单位:
Cross-talk between cytokine and pathogen recognition receptor networks in the pathogenesis of gastric cancer
-
批准号:nhmrc : 490956
-
项目类别:NHMRC Project Grants
-
资助金额:$11.66万
-
财政年份:2008
-
负责人:A/Pr Ashley Mansell
-
依托单位:
Suppression of Immune Toll-like receptor (TLR) signaling by Hepatitis B e Antigen (HBeAg)
-
批准号:nhmrc : 491017
-
项目类别:NHMRC Project Grants
-
资助金额:$36.16万
-
财政年份:2008
-
负责人:A/Pr Ashley Mansell
-
依托单位:
Negative regulation and immune subversion of Toll-like receptor signaling pathways
-
批准号:nhmrc : 465116
-
项目类别:Career Development Fellowships
-
资助金额:$31.41万
-
财政年份:2007
-
负责人:A/Pr Ashley Mansell
-
依托单位:
The role of Mal in Toll-like receptor signal transduction of the pro-inflammatory response.
-
批准号:nhmrc : 334023
-
项目类别:NHMRC Project Grants
-
资助金额:$31.51万
-
财政年份:2005
-
负责人:A/Pr Ashley Mansell
-
依托单位:
国内基金
海外基金
登录
查看更多内容
缺氧诱导因子(HIF)-2α转录抑制树突状细胞CD36表达减轻肾脏缺血再灌注损伤的机制
-
批准号:82370751
-
项目类别:面上项目
-
资助金额:49.00万元
-
批准年份:2023
-
负责人:张明
-
依托单位:
基于压力敏感肾单位微流控芯片的肾上皮细胞CAT1-mTOR通路在梗阻性肾损伤中的作用机制研究
-
批准号:82370678
-
项目类别:面上项目
-
资助金额:49.00万元
-
批准年份:2023
-
负责人:林厚维
-
依托单位:
基于影像代谢重塑可视化的延胡索酸水合酶缺陷型肾癌危险性分层模型的研究
-
批准号:82371912
-
项目类别:面上项目
-
资助金额:48.00万元
-
批准年份:2023
-
负责人:吴广宇
-
依托单位:
BMSCs 源 exosome 通过MFG-E8/αvβ3integrin 干预新生鼠梗阻性肾损伤的机制研究
-
批准号:19ZR1432800
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2019
-
负责人:姜大朋
-
依托单位:
EPO-EPOR通路在肾癌靶向药物耐药机制中的作用及阻断此通路的意义
-
批准号:81172418
-
项目类别:面上项目
-
资助金额:65.0万元
-
批准年份:2011
-
负责人:龚侃
-
依托单位:
新型连接蛋白Card9调节肾癌NF-κB的分子机制研究
-
批准号:81101519
-
项目类别:青年科学基金项目
-
资助金额:25.0万元
-
批准年份:2011
-
负责人:毕良宽
-
依托单位:
黄芪当归合剂有效组分抗氧化应激作用的细胞信号转导调控机制研究
-
批准号:81041001
-
项目类别:专项基金项目
-
资助金额:10.0万元
-
批准年份:2010
-
负责人:王玉
-
依托单位:
肾损伤分子-1介导肾小管上皮细胞吞噬作用的病生理意义及机制研究
-
批准号:81070549
-
项目类别:面上项目
-
资助金额:37.0万元
-
批准年份:2010
-
负责人:杨莉
-
依托单位:
肾癌干细胞的实验研究
-
批准号:81041065
-
项目类别:专项基金项目
-
资助金额:10.0万元
-
批准年份:2010
-
负责人:赵升田
-
依托单位: