TAF8 is a suppressor of cell death

TAF8 是细胞死亡的抑制剂

• 批准号: nhmrc : 1084504
• 负责人: A/Pr Anne Voss
• 金额: $ 38.04万
• 依托单位: The Walter and Eliza Hall Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/taf8-suppressor-cell-death/519011
• 关键词: TAF8; suppressor; cell; death

TAF8 is a small protein that is associated with the general transcriptional apparatus. TAF8 is not an essential part of the general transcriptional machinery, but rather a regulatory molecule that appears to dictate how the machinery is used to express different genes. The absence of TAF8 leads to expression of genes controlling cell death. Since the avoidence of cell death is essential to the development of cancer these results will lead to a better understanding of how cancer develops.

TAF8是一种与一般转录装置相关的小蛋白。TAF8不是一般转录机制的重要组成部分，而是一种调控分子，似乎决定了该机制如何用于表达不同的基因。TAF8的缺乏导致控制细胞死亡的基因的表达。由于避免细胞死亡对于癌症的发展至关重要，这些结果将有助于更好地了解癌症的发展方式。