Market assessment for a novel instrument based on surface plasmon resonance

基于表面等离子体共振的新型仪器的市场评估

• 批准号: 428629-2011
• 负责人: Masson, JeanFrancois
• 金额: $ 1.09万
• 依托单位: Université de Montréal
• 依托单位国家: 加拿大
• 项目类别: Idea to Innovation
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=496323
• 关键词: Market; assessment; novel; instrument; based

A market assessment is necessary to establish the priorities that will dictate the next steps for the development of a novel Surface Plasmon Resonance (SPR) instrument. Our prototype SPR device is label-free, inexpensive, exhibits high sensitivity and selectivity and is suited for the analysis of biomarkers in crude biofluids. These achievements were the consequence of a novel SPR instrument design based on a dove prism, and a sensing chip technology based on micropatterned gold films and anti-fouling peptide surface chemistry. The prototype we have developed is portable and thus, is suited for point-of-measurement applications such as point-of-care diagnostics or on-site detection of contaminants or pathogens. The resolution of our portable SPR instrument rivals the one obtained with more expensive lab-based SPR instruments. Our sensing chip technology improves the sensitivity by more than a factor of 3 relative to other commercial sensing technologies, reducing error. In addition, our peptide monolayers prevent fouling of the sensing chip, and thus, false positive responses, which is necessary for point-of-care biomedical applications.

市场评估是必要的，以建立优先事项，将决定下一步的发展，一种新的表面等离子体共振（SPR）仪器。我们的原型SPR装置是无标记的，廉价的，具有高灵敏度和选择性，并适用于原油生物流体中的生物标志物的分析。这些成就是基于鸽子棱镜的新型SPR仪器设计和基于微图案化金膜和防污肽表面化学的传感芯片技术的结果。我们开发的原型是便携式的，因此适用于测量点应用，例如护理点诊断或污染物或病原体的现场检测。我们的便携式SPR仪器的分辨率与更昂贵的实验室SPR仪器获得的分辨率相媲美。相对于其他商业传感技术，我们的传感芯片技术将灵敏度提高了3倍以上，从而减少了误差。此外，我们的肽单层可以防止传感芯片的污染，从而防止假阳性反应，这对于即时护理生物医学应用是必要的。