HEN1 is a regulator of piRNA metabolism, transcriptional regulation and mammalian male fertility

HEN1 是 piRNA 代谢、转录调节和哺乳动物雄性生育力的调节因子

• 批准号: DP120101703
• 负责人: Prof Moira O'Bryan
• 金额: $ 24.65万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP120101703
• 关键词: HEN1; regulator; piRNA; metabolism; transcriptional

This project is to define the biochemistry of a previously uncharacterized protein in male fertility using a unique mouse model and innovative DNA and protein technologies. This project will define a novel, and essential, pathway for male fertility and may ultimately have relevance to the maintenance of health or improving fertility.

该项目是使用独特的小鼠模型和创新的DNA和蛋白质技术来定义以前未表征的蛋白质在男性生育力中的生物化学。该项目将为男性生育力定义一种新颖且重要的途径，并最终可能与维持健康或提高生育力相关。