The genetic causes of male infertility
The genetic causes of male infertility
批准号:
nhmrc : 1120356
负责人:
Prof Moira O'Bryan
金额:
$106.14万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 2021-12-31
中文摘要
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英文摘要
6% of Australian men are infertile. Of these cases 50% are thought to be genetic in origin. Within this project we will replicate high-confidence genetic variants associated with human male infertility in the mouse. Doing so will allow the assignment of definitive genotype-phenotype correlations and the formulation of high confidence advice for clinicians and patients. It will also provide a means to define the mechanism of action and the tools for future pro-fertility treatments.
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会议论文
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财政年份:2020
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批准号:nhmrc : 1138014
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财政年份:2018
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依托单位:
Mechanisms of manchette function
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批准号:DP180100533
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项目类别:Discovery Projects
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资助金额:$24.37万
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财政年份:2018
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负责人:Prof Moira O'Bryan
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依托单位:
Finding the missing katanin required for male fertility
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批准号:nhmrc : GNT1138014
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项目类别:Project Grants
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资助金额:$41.72万
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财政年份:2018
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负责人:Prof Moira O'Bryan
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依托单位:
A novel microtubule severing protein involved in male germ cell biology
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批准号:DP160100647
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项目类别:Discovery Projects
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资助金额:$27.84万
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财政年份:2016
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负责人:Prof Moira O'Bryan
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依托单位:
Male fertility and health
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批准号:nhmrc : GNT1058356
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项目类别:Research Fellowships
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资助金额:$72.76万
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财政年份:2014
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负责人:Prof Moira O'Bryan
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依托单位:
Male germ cell development - fertility and health
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批准号:nhmrc : 1058356
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项目类别:Research Fellowships
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资助金额:$50.9万
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财政年份:2014
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负责人:Prof Moira O'Bryan
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依托单位:
HEN1 is a regulator of piRNA metabolism, transcriptional regulation and mammalian male fertility
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批准号:DP120101703
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项目类别:Discovery Projects
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资助金额:$24.65万
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财政年份:2012
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负责人:Prof Moira O'Bryan
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依托单位:
A novel DNA damage repair protein as a regulator of DNA double strand break repair and genome integrity
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批准号:DP110102288
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项目类别:Discovery Projects
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资助金额:$25.33万
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财政年份:2011
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负责人:Prof Moira O'Bryan
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依托单位:
Uncoupled Research Fellowship
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批准号:nhmrc : 545805
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项目类别:NHMRC Research Fellowships
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资助金额:$42.79万
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财政年份:2009
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负责人:Prof Moira O'Bryan
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依托单位:
The identification of male meiosis genes using a new mouse line and human genome scans for gene copy number variations
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批准号:nhmrc : 490916
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项目类别:NHMRC Project Grants
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资助金额:$40.33万
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财政年份:2008
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负责人:Prof Moira O'Bryan
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依托单位:
Research Fellowship - Grant ID:384132
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批准号:nhmrc : 384132
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项目类别:NHMRC Research Fellowships
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资助金额:$21.52万
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财政年份:2006
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负责人:Prof Moira O'Bryan
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依托单位:
The Biology of Sperm Tail Development
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批准号:nhmrc : 143781
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项目类别:Career Development Fellowships
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资助金额:$20.87万
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财政年份:2001
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负责人:Prof Moira O'Bryan
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依托单位:
The expression and regulation of nitric oxide synthases in the male reproductive tract
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批准号:nhmrc : 967135
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项目类别:Early Career Fellowships
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资助金额:$14.75万
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财政年份:1996
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负责人:Prof Moira O'Bryan
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依托单位:
海外基金