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Self-assembly of DNA and biologically enabled polymers

Self-assembly of DNA and biologically enabled polymers
DNA 和生物聚合物的自组装
批准号:
217563-2008
负责人:
Sleiman, Hanadi
金额:
$4.01万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-01-01 至 2013-12-31

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英文摘要
Our research group focuses on the development of DNA-mediated methods to pattern materials with high precision on the nanometer scale. Towards this goal, we have examined the use of synthetic molecules to direct DNA self-assembly. This approach has resulted in a unique range of previously unreported materials, from discrete assemblies of gold nanoparticles and transition metals with fine positioning of each component, to 3D-DNA capsules of any geometry and size, to new forms of DNA in which multiple strands (rather than two) come together. In addition, we have shown, for the first time, the use of small molecules to switch and modify the structure of these assemblies in real-time, and to change the outcome of the self-assembly.
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