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Dissecting the hematopoietic hierarchy and function using inherited human disease models of hematopoietic stem cell/progenitor loss

Dissecting the hematopoietic hierarchy and function using inherited human disease models of hematopoietic stem cell/progenitor loss
使用造血干细胞/祖细胞丢失的遗传性人类疾病模型剖析造血层次结构和功能
批准号：
357973
负责人：
Dror Yigal
金额：
$61.86万
依托单位：
Hospital for Sick Children (Toronto)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-10-01 至 2020-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=357973&lang=en
关键词：
Bone Marrow Failure Genetic Disorders Genomics Hematopoiesis Hematopoietic Stem Cells Immunophenotyping Mass Cytometry

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英文摘要
The bone marrow (BM) makes millions of blood cells every day via a complex multistep process. White blood cells fight infections, platelets prevent bleeding and red cells deliver oxygen; all are crucial to sustain life. Reduced blood formation is a common
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