MALDI mass spectrometer

MALDI质谱仪

• 批准号: RTI-2017-00724
• 负责人: Woolley, Andrew
• 金额: $ 10.93万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=616753
• 关键词: MALDI; mass; spectrometer

Matrix Assisted Laser Desorption Ionization (MALDI) mass spectrometry allows the rapid characterization of large molecules such as peptides, proteins and polymers. There is currently no MALDI mass spectrometer in the chemistry department at the University of Toronto. There are 10 research groups from within the chemistry department that require student access to a MALDI-MS instrument on a daily basis to realize their research goals. Due to the complete breakdown of our current instrument, we now have no internal facility for such measurements and have had to seek specialized service facilities to run these analyses for us. Much of our work depends on this technique. Access to a MALDI mass spectrometer would enable hands-on training, develop skills in MS interpretation, and greatly enhance the pace of scientific discovery in a diverse group of research programs.

基质辅助激光解吸电离（MALDI）质谱法可以快速表征大分子，如肽、蛋白质和聚合物。多伦多大学化学系目前没有MALDI质谱仪。化学系内有10个研究小组，要求学生每天使用MALDI-MS仪器来实现他们的研究目标。由于我们目前的仪器完全故障，我们现在没有内部设施进行此类测量，不得不寻求专门的服务设施为我们进行这些分析。我们的许多工作都依赖于这种技术。获得MALDI质谱仪将使实践培训，发展MS解释技能，并大大提高科学发现的步伐，在一个不同的研究计划组。