Robotic breast cancer surgery

乳腺癌影响女性一生中的1/8，是女性患乳腺癌的第二大原因。 女性癌症相关死亡。理想的治疗方法是乳房保乳手术。 早期切除癌症，同时保留健康的乳房部位。沃斯电流 平均每三名接受保乳手术的女性中就有一名接受乳房切除手术 由于肿瘤切除不完全，手术至少需要再做一次手术。 重复手术会增加术后并发症、化妆品受损的风险， 延迟的放射治疗，增加的心理痛苦，增加的费用和风险 正在接受第二次全身麻醉。重复手术通常会导致乳房全切除， 对于一个期待保乳治疗的患者来说，这是一次痛苦的经历。 由于早期乳腺癌摸不到或看不见，外科医生倾向于应用 目标肿瘤周围的巨大安全边缘，并切除大量健康的乳房 组织。在目前的实践中，高达40%的接受保乳手术的患者 经历过需要手术重建的严重乳房畸形，但超过一半的 这些妇女由于缺乏重建手术能力而得不到治疗。 在这项研究中，我们的目标是开发下一代保乳手术NaviKnife 导航系统，以最小的组织损失实现肿瘤的完全切除。纳维克尼夫 建立在新的多参数超声成像的基础上，在 肿瘤切除和新的实时代谢组织分型以识别和追踪肿瘤 在一个简单的机械臂引导下，切除过程中的边界。NaviKnife协助 外科医生进行精确的肿瘤切除，并允许系统地探查切除腔 对于残留的癌症，如有必要，指导外科医生有针对性地剃除腔壁 以最小的健康组织损失，从而保证在手术前完全切除肿瘤 伤口闭合了。

Breast cancer affects 1 in 8 women during their lives and is the second-leading cause of female cancer related deaths. The ideal treatment is breast-conservation surgery during its early stage to remove the cancer while conserving healthy parts of the breast. Wirth current resection methods, on average, one out of every three women undergoing breastconservation surgery needs at least one additional surgery due incomplete tumor resection. Repeat surgery leads to increased risk of postoperative complications, impaired cosmetics, delayed radiation therapy, increased psychological distress, and increased costs and risks of undergoing a second general anesthesia. Repeat surgery often leads to full mastectomy, which is a traumatic experience for a patient who expected a curative treatment with breastconservation. As early stage breast cancer is not palpable or visible, surgeons tend to apply generous safety margins around the target tumor and remove a great deal of healthy breast tissue. In current practice, up to 40% of patients who undergo breast-conservation surgery experience severe breast deformity that requires surgical reconstruction, but over half of these women do not get treated due to lack reconstructive surgical capacity. In this research, we aim to develop NaviKnife, a next-generation breast conserving surgery navigation system to achieve complete tumor resection with minimal tissue loss. NaviKnife builds on novel multiparametric ultrasound imaging to accurately target the cancer prior to resection and novel real-time metabolomic tissue typing to identify and trace the tumor boundary during resection while guided by a simple robotic arm. NaviKnife assists the surgeon in precise tumor resection and allows for systematic probing of the resection cavity for residual cancer and, if necessary, guides the surgeon in targeted shaving of the cavity wall with minimal loss of healthy tissue, thus guaranteeing complete tumor removal before the wound is closed.