Optimization of Genecis' Polyhydroxyalkanoate Formulation through Adjustment of Hydroxybutyrate, Hydroxyvalerate Ratios

通过调整羟基丁酸酯、羟基戊酸酯比例优化 Genecis 聚羟基脂肪酸酯配方

• 批准号: 558321-2020
• 负责人: Sheikhzadeh, Mehdi
• 金额: $ 2.19万
• 依托单位: Lambton College of Applied Arts and Technology
• 依托单位国家: 加拿大
• 项目类别: Applied Research and Development Grants - Level 1
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=706509
• 关键词: Optimization; Genecis; Polyhydroxyalkanoate; Formulation; through

Genecis Bioindustries is a biotechnology company that converts food waste into PHA (polyhydroxyalkanoate) biodegradable plastics and other high value materials. Since 2017, they have rapidly scaled operations from the laboratory bench-scale at University of Toronto to operating out of a 4,000 sq/ft functional pilot facility in Scarborough, Ontario. Recently, Genecis has completed an industrial-scale 1000 L fermentation validation at the National Research Council in Montreal, filed 2 patents, and established an in-house materials testing laboratory. Genecis has also completed food waste to PHA conversion technology, which involves using mixed organic feed stock with Genecis proprietary bacteria. This is significant as there is not commercialized technology in the world that can currently produce PHAs from non-union sugar sources like organic waste. This collaborative project with Lambton college will focus on the adjustment of %HV and its effect on material properties and processability. To achieve the overall goal of the project, a series of physical, mechanical, rheological, and chemical analyses to characterize the different grades of PHBVs (poly-3-hydroxybutyrate-co-3-hydroxyvalerate) will be conducted, as well as, multiple experiments to fine-tune the created higher %HV PHBVs and polymer manufacturing trials for PHBV composite product applications. The success of the project will lead to potentially, $850,000 immediate revenues, and an additional $6 million in recurring purchase orders. After the successful commercialization of results, it is estimated that sales of $300,000 plus $3 million in purchase orders in Canada as well as $1,500,000 with an additional $6 million in purchase orders internationally will occur over 2-3 years. With increased level of production, it is estimated to create new or supporting positions of up to 10 full time positions. Since, this polymer has a strong appeal in a worldwide single-plastic market, there is potential for sales to grow significantly more over time.

Genecis Bioindustries是一家生物技术公司，将食物垃圾转化为PHA（聚羟基链烷酸酯）生物降解塑料和其他高价值材料。自2017年以来，他们已经迅速将业务规模从多伦多大学的实验室规模扩大到安大略斯卡伯勒的4，000平方英尺功能试点设施。最近，Genecis在蒙特利尔的国家研究理事会完成了工业规模的1000 L发酵验证，申请了2项专利，并建立了内部材料测试实验室。Genecis还完成了食物垃圾转化为PHA的技术，该技术涉及使用含有Genecis专有细菌的混合有机原料。这是重要的，因为目前世界上还没有商业化的技术可以从非工会糖源如有机废物中生产PHA。 这个与兰顿学院的合作项目将重点关注%HV的调整及其对材料性能和加工性能的影响。为了实现该项目的总体目标，将进行一系列物理，机械，流变和化学分析，以表征不同等级的PHBV（聚-3-羟基丁酸酯-co-3-羟基戊酸酯），以及多个实验，以微调所产生的较高%HV PHBV和用于PHBV复合产品应用的聚合物制造试验。 该项目的成功将带来潜在的85万美元的直接收入，以及额外的600万美元的经常性采购订单。在成果成功商业化后，估计在2-3年内，加拿大的销售额为30万美元，采购订单为300万美元，国际采购订单为150万美元，采购订单为600万美元。随着生产水平的提高，预计将创造多达10个全职职位的新职位或支持职位。由于这种聚合物在全球单一塑料市场中具有强大的吸引力，因此随着时间的推移，销售额有可能大幅增长。