Development of Polymer-based flow cytometry reagents

聚合物流式细胞术试剂的开发

• 批准号: 561149-2020
• 负责人: Seferos, Dwight
• 金额: $ 1.82万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Alliance Grants
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=719740
• 关键词: Development; Polymer; based; flow; cytometry

In this collaborative project between the University of Toronto and BD, we will develop new polymer-based fluorophores for enhanced multicolour flow cytometry. Breakthroughs in polymer design will lead to new world-wide product lines for BD. BD is widely regarded as a leader in the design and commercialization of fluorophores for multicolour flow cytometry and already has several successful product lines, including the Brilliant VioletTM and Brilliant UVTM fluorophores, considered market leaders. The Seferos group has deep expertise in the controlled 'living' synthesis and study of semiconducting polymers, polymer photophysics, and polymer characterization techniques. BD Biosciences seeks to expand their market presence by developing brighter and more well-defined polymer based dyes to support their instrumentation businesses. This partnership is thus ideally poised to make significant breakthroughs in fluorophore design for enhanced multicolour flow cytometry.

在多伦多大学和BD之间的这个合作项目中，我们将开发新的基于聚合物的荧光团，用于增强多色流式细胞术。聚合物设计的突破性进展将为BD带来新的全球产品线。BD被广泛认为是多色流式细胞术荧光团设计和商业化的领导者，已经拥有几条成功的产品线，包括被认为是市场领导者的Brilliant VioletTM和Brilliant UVTM荧光团。Seferos集团在半导体聚合物的可控“活性”合成和研究、聚合物微物理和聚合物表征技术方面拥有深厚的专业知识。BD Biosciences寻求通过开发更明亮和更明确的聚合物染料来扩大其市场份额，以支持其仪器业务。因此，这种合作关系有望在增强型多色流式细胞术的荧光团设计方面取得重大突破。