Nuclear magnetic resonance (NMR) of molecules and cells in media with 'tunable' anisotropy: high rank-spins, z-spectra, (pro)chiral discrimination, peptide L-to-D isomerase

具有“可调”各向异性的介质中分子和细胞的核磁共振 (NMR)：高阶自旋、z 谱、（前）手性辨别、肽 L 至 D 异构酶

• 批准号: DP110103020
• 负责人: Em/Prof Philip Kuchel
• 金额: --
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP110103020
• 关键词: Nuclear; magnetic; resonance; NMR; molecules

This project will build on this team's invention of a stretched-gel method that reports on molecular composition and the geometrical arrangement of atoms into mirror image arrays, using nuclear magnetic resonance spectroscopy. The project will use the methodology to determine roles of a platypus venom enzyme that carries out stereoscopic interconversions, even in humans.

该项目将建立在该团队发明的拉伸凝胶方法的基础上，该方法使用核磁共振光谱法报告分子组成和原子的几何排列成镜像阵列。该项目将使用该方法来确定鸭嘴兽毒液酶的作用，该酶甚至在人类中进行立体相互转换。