Microprobes for Characterization of Immobilized Cell Systems

这项研究涉及的微探针的发展， 固定化细胞系统。 固定化细胞在一个环境中 这与自由细胞的情况截然不同， 可能会改变他们的代谢行为。 对此的研究 微环境效应受到限制， 微型实验技术。 为了满足这一需求， 一个项目是开发能够测量氧化还原的微探针 潜在的和重要的细胞代谢物的浓度， 固定化细胞的紧邻区域。 这些新的微探针 将提供新的研究能力，这将大大扩大 固定化细胞系统的研究范围。

This study involves the development of microprobes for characterization of immobilized cell systems. Immobilized cells are in an environment which is drastically different from that of free cells, and this is likely to change their metabolic behavior. Studies on this microenvironmental effect have been constrained by the limitations of experimental techniques in micro-scale. To fill this need, this project is developing microprobes which are capable of measuring redox potential and the concentrations of important cellular metabolites in the immediate vicinity of the immobilized cells. These new microprobes will provide new research capabilities, which will significantly expand the scope of investigation into the immobilized cell systems.