Engineering Research Equipment Grant: Optical Systems for Microprobe Research

固定化细胞所处的环境 这很可能会改变它们的代谢 行为 对这种微环境效应的研究已经 由于实验技术的局限性， 微观尺度。 微探针和微光电二极管将被开发用于 测量氧化还原电位和重要细胞的浓度， 在固定化细胞附近的代谢。 一 1500倍体视显微镜和光纤单色仪 将需要输入/输出能力，以促进发展 的探测器。 这些新的微探针将提供新的研究 能力，这将大大扩大调查范围 进入固定化细胞系统。

Immobilized cells are in an environment which is drastically different from that of free cells, and this is likely to change their metabolic behavior. Studies on this microenvironmental effect have been constrained by the limitations of experimental techniques on a micro-scale. Microprobles and Micro-optodes will be developed for measuring redox potential and the concentrations of important cellular metabolities in the immediate vicinity of the immobilized cells. A 1500X stereomicroscope and a monochromator with optical fiber input/output capabiliity will be required to facilitate the development of the probes. These new microprobes will provide new research capabilities, which will signficantly expand the scope of investigation into the immobilized cell systems.