Protein Separations: A Thermodynamic Approach

这个项目的目标是为蛋白质分离的分析和设计开发一个定量的热力学基础，可与化学加工工业中常规应用于非生化分离的分离相媲美。理论工作将由涉及以下几个方面的实验加以补充：结构和结构的表征功能性蛋白质特性，热力学性质的测量以验证热力学描述的有效性，以及分离实验，以评估基于热力学模型的性能预测。

The objective of this project is to develop a quantitative thermodynamic basis for the analysis and design of protein separations, comparable to that which is routinely applied to non-biochemical separations in the chemical process industries. The theoretical work will be complemented by experiments addressing several aspects: characterization of structural and functional protein properties, measurement of thermodynamic properties to verify the validity of the thermodynamic descriptions, and separations experiments to evaluate the predictions of performance based on the thermodynamic models.