Electronics Upgrade of an NMR Spectrometer

这项提议是要求提供资金，以升级现有已有九年历史的Bruker WM-400 MHz核磁共振(核磁共振)光谱仪的电子设备和数据处理能力。将成为该仪器主要用户的五个化学研究小组在其有机和无机合成计划中需要核磁共振作为辅助，以鉴定产品和确定产品结构。这项拟议的工作需要一台具有可变温度和复杂脉冲控制的现代多核核磁共振光谱仪，用于当前和未来的2D FT核磁共振实验。目前的仪器是堪萨斯州立大学校园内唯一的研究级核磁共振仪器，几乎预订满了，数据处理和数据存储系统有限、过时，在提供去耦合光谱或按需执行DEPT、NOESY和COSY实验方面遇到了越来越大的困难。四个主要用户中的两个目前得到了国家科学基金会的奖励支持。化学、生物化学、食品和营养与谷物科学系的其他教员也将从这次升级中受益，他们被列为“其他”用户。%这项建议将有助于购买现代核磁共振(核磁共振)光谱仪。该仪器是堪萨斯州立大学从事化学研究的教职员工的必备工具。该仪器提供了重要的信息，在大多数情况下可用于确定新合成的分子的几何和/或分子结构。

This proposal is a request for funds to upgrade the electronics and the data processing capability of an existing nine- year-old Bruker WM-400 MHz nuclear magnetic resonance (NMR) spectrometer. The five chemistry research groups that will be the principal users of this instrument require NMR as an aid in their organic and inorganic synthetic programs to identify products and to determine product structures. The proposed work requires a modern multinuclear NMR spectrometer with variable temperature and sophisticated pulse control for current and future 2D FTNMR experiments. The current instrument, which is the only research grade NMR on the campus at Kansas State University, is nearly maximally booked, has a limited, obsolete data processing and data storage system, and is encountering increasing difficultes in providing decoupled spectra or in performing DEPT, NOESY, and COSY experiments upon demand. Two of the four principal users are currently supported by awards from the National Science Foundation. Other faculty in the departments of Chemistry, Biochemistry, Foods and Nutrition and Grain Science will also benefit from this upgrade and they are listed as "other" users. %%% This proposal will assist in the purchase of a modern nuclear magnetic resonance (NMR) spectrometer. This instrument is an essential tool for faculty members at Kansas State University engaged in chemical research. The instrument provides important information which in most cases can be used to determine the geometric and/or molecular structure of newly synthesized molecules.