Multilabel Imager for Genomics

BioTraces Inc. （BT Inc.）开发了一种超灵敏的定量系统，可用于大量同位素。该系统支持标签复用；该家族中的许多共居同位素可以同时定量，允许将标记样品池化或将标记探针试剂池化用于多个目标。拟议的研究将增加系统的二维（2D）空间分辨率，以支持核酸定量和分离，包括测序。由于广泛的多路复用能力和优越的灵敏度，该技术将大大提高分馏/定量任务中的样品吞吐量。

BioTraces Inc. (BT Inc.) has developed an ultrasensitive quantitation system which can be used with a large family of isotopes. This system supports label multiplexing; many co- resident isotopes in the family can be quantitated simultaneously, allowing either the pooling of labeled samples of the pooling of distinctly labeled probe reagents for multiple targets. The proposed research will add two dimensional (2D) spatial resolution to the capabilities of the systems, in support of nucleic acid quantitation and fractionation, including sequencing. Because of the extensive multiplexing capabilities and superior sensitivity, the proposed technique will greatly increase sample throughput in fractionation/quantitation tasks.