Acquisition and Upgrade of NMR Spectrometers

化学研究仪器计划的这一奖项将帮助马里兰大学帕克分校的化学和生物化学系购买新的400 MHz核磁共振光谱仪，并升级现有的500 MHz核磁共振光谱仪。将使用新设备的项目包括：生物活性物质的合成、三氯乙烯抗生素复合体的化学和生物学、机械酶学、金属锌离子、生物大化合物和多肽糖基化。核磁共振波谱是化学家用来解释分子结构的最有力的工具。它被用来识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱是必不可少的。这些核磁共振研究的结果在聚合物和催化等领域以及生物学中都是有用的。

This award from the Chemistry Research Instrumentation Program will help the Department of Chemistry and Biochemistry of the University of Maryland College Park purchase a new 400 MHz NMR spectrometer and to upgrade an existing 500 MHz NMR spectrometer. The projects that will use the new equipment include: Synthesis of bioactive substances, chemistry and biology of the trichothecene antibiotic complex, mechanistic enzymology, metallated zintl ions, biological macrocompounds, and peptide glycosylation. Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research. The results from these NMR studies are useful in areas such as polymers and catalysis and in biology.