Acquisition of a 500-MHz NMR Spectrometer Console Upgrade and Cyberinfrastructure Capability

获得 500 MHz NMR 波谱仪控制台升级和网络基础设施能力

• 批准号: 0741968
• 负责人: Robert Continetti
• 金额: $ 60.27万
• 依托单位: University of California-San Diego
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-02-01 至 2013-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0741968&HistoricalAwards=false
• 关键词: Acquisition; 500; MHz; NMR; Spectrometer

With this award from the Chemistry Research Instrumentation and Facilities: Multi User program (CRIF:MU), the Department of Chemistry at the University of California-San Diego will acquire a cyber-enabled 500 MHz Nuclear Magnetic Resonance (NMR) spectrometer with cyber-infrastructure capability. The spectrometer will be utilized in various research projects in areas such as organotransition metal chemistry, development of polycarbonate doping resins for ligand deposition on commercially available CDs, nonribosomal peptide biosynthesis, chiral metal-organic frameworks and metalloprotein inhibitors, natural products from marine sources, symmetry of hydrogen bonds, isotope effects on acidity, and fluorescent nucleoside analogues.Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in synthetic organic/inorganic chemistry and biochemistry.

凭借化学研究仪器和设施：多用户计划（CRIF：MU）的这一奖项，加州大学圣地亚哥分校化学系将获得一台具有网络基础设施能力的网络支持的500 MHz核磁共振（NMR）光谱仪。该光谱仪将用于各种研究项目，如有机过渡金属化学，聚碳酸酯掺杂树脂的开发，用于商业上可获得的CD上的配体沉积，非核糖体肽生物合成，手性金属有机框架和金属蛋白抑制剂，海洋来源的天然产物，氢键的对称性，同位素对酸度的影响，核磁共振（NMR）光谱是化学家用来阐明分子结构的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于从事前沿研究的化学家来说，使用最先进的NMR光谱仪是必不可少的。这些NMR研究的结果将对合成有机/无机化学和生物化学产生影响。