Acquisition of a Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometer

9802930 Shea该合同为购买基质辅助激光解吸电离飞行时间质谱仪(MALDI-TOF-MS)提供部分支持。这种仪器对加州大学欧文分校正在进行的许多材料研究项目至关重要，这些项目包括聚合物科学、材料和合成化学、蛋白质工程和疾病研究。UCI没有提供MALDI-TOF-MS。这个校园的化学系迅速扩大了教师队伍，产生了更多类型的样本，同时样本数量也在增加。目前在该设施中的两个磁扇区系统完全致力于为有机合成提供高分辨率数据。该仪器将在多用户环境中使用。MALDI-TOF-MS关键的项目包括：多同系化以形成混合疏水/疏水聚合物和合成有机硅单体；不完全缩合倍半硅氧烷笼子的研究及其在表面反应模型、杂化无机/有机聚合物和树枝状大分子中的应用；合成光致发光和氧化还原活性树枝状大分子和多金属化合物，在纳米级光子和电子器件中有潜在的应用；稀土元素化学以及稀土配合物介导的聚合物形成机理的形成和理解。大约25名教师、140名研究生和50名博士后将可以使用该仪器。%*

9802930SheaThis award provides partial support for the purchase of a matrix assisted laser desorption ionization time of flight mass spectrometer (MALDI-TOF-MS). This instrumentation is essential to many materials research programs being undertaken on the University of California, Irvine campus which include programs in polymer science, material and synthetic chemistry, protein engineering, and disease research. No MALDI-TOF-MS is available at UCI. The chemistry department on this campus has rapidly expanded its faculty generating many more types of sample as well as increasing sample numbers. The two magnetic sector systems now in the facility are fully committed providing high resolution data for organic synthesis. The instrument will be used in a multi-user environment. Projects in which the MALDI-TOF-MS is essential include: polyhomologation to form mixed hydrophilip/hydrophobic polymers and synthesis of organosiliconate monomers; research on incompletely condensed silsesquioxane cages and there use in surface reactivity models, hybrid inorganic/organic polymers and dendrimers; synthesis of photoluminescent and redox-active dendrimers and multimetallic compounds with potential applications in nanoscale photonic and electronic devices; lanthanide chemistry and the formation and understanding of the mechanisms of polymer formation as mediated by lanthanide complexes. Approximately 25 faculty, 140 graduate students, and 50 postdoctorals will have access to this instrument.%%%***