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Developmental analysis of extinction of learned fear in rats

Developmental analysis of extinction of learned fear in rats
大鼠习得性恐惧消退的发育分析
批准号:
DP0985554
负责人:
Prof Rick Richardson
金额:
$15.6万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2012-12-31

项目摘要

项目成果

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中文摘要
翻译
该项目旨在更好地了解物种灭绝(即物种灭绝)。老鼠习得性恐惧的丧失。消退是暴露疗法的基础过程,暴露疗法是目前治疗焦虑症最有效的方法。虽然大多数焦虑症都是在生命的早期被诊断出来的,但我们对整个发展过程中恐惧的消失知之甚少。然而,最近的研究结果表明,在消除恐惧方面存在根本性的发展差异,本项目更详细地探讨了这些差异。通过这样做,该项目旨在增加我们对如何抑制恐惧的理解,并可能最终导致针对焦虑症的适龄治疗方法的发展。
英文摘要
This project aims to gain a better understanding of extinction (ie., loss) of learned fear in rats. Extinction is the process underlying exposure therapy, which is the most effective current treatment for anxiety disorders. Although most anxiety disorders are first diagnosed relatively early in life, we know very little about extinction of fear across development. However, recent findings have suggested that there are fundamental developmental differences in the extinction of fear, and the present project explores these differences in greater detail. By doing so, the project aims to increase our understanding of how fears can be inhibited, and may eventually lead to the development of age-appropriate treatments for anxiety disorders.
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Dissecting the Brain Circuitry Shaping Fear Regulation Across Development
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Developmental differences in the role of the medial prefrontal cortex in fear regulation
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