MRI: Acquisition of a 600 MHz Nuclear Magnetic Resonance Spectrometer

俄勒冈州立大学化学系将从主要研究仪器计划(MRI)获得这一奖项，以获得一台600 MHz核磁共振(核磁共振)光谱仪。核磁共振波谱仪将用于几个研究项目，包括1)合成复杂的、具有生物活性的天然产物，2)从微生物中生物合成具有生物活性的天然产物，以及3)不对称有机合成的新方法。600兆赫核磁共振波谱仪将被安置在化学系核磁共振设施中，许多潜在的用户可以很容易地使用。核磁共振波谱是化学家可以用来阐明分子结构的最强大的工具之一。它被用来识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱仪是必不可少的。高场核磁共振将提供更高的分散度和灵敏度，以便更好地检测本研究中提出的复杂分子合成中的中间体和产物。

With this award from the Major Research Instrumentation program (MRI), the Chemistry Department at Oregon State University will acquire a 600 MHz Nuclear Magnetic Resonance (NMR) spectrometer. The NMR spectrometer will be utilized in several research projects including 1) synthesis of complex, biologically-active natural products, 2) biosynthetic studies of biologically active natural products from microorganisms, and 3) new methods in enantioselective organic synthesis. The 600 MHz NMR spectrometer will be housed in the Chemistry Department NMR Facility, readily accessible by many potential users.Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The high field NMR will provide increased dispersion and sensitivity to better detect intermediates and products in the synthesis of complex molecules proposed in this study.