MRI: Acquisition of a Liquid Chromatography Electrospray Ionization (LC-ESI) Mass Spectrometer for Undergraduate Research

该主要研究仪器奖资助了Hiram学院的液相色谱电喷雾电离质谱仪（LC ESI-MS）。新的LCMS系统提供了一种独特的方法来阐明复杂实验中的分子结构，并将帮助Hiram学院的教师识别生物样品（血浆和昆虫）中的脂肪酸，检测次生植物代谢物，分析大氯化化合物，并区分野生型和突变型非洲爪蟾的代谢谱。海勒姆学院的研究项目处于各自领域的前沿，将被用作本科生课堂课程和独立研究项目的培训基地。lms将作为海勒姆学院（Hiram College）合作项目“课堂研究”（Research in The Classroom）的一部分，让学生在课程中体验真实世界的研究问题。这样的方法培养了每个学生在课堂上进行实地或实验室研究时的独立思考。与LCMS合作进行的研究结果将通过摘要和同行评审的出版物，以及学生和教师在专业会议上的积极参与，广泛传播。

This Major Research Instrumentation award funds the acquisition of a Liquid Chromatography Electrospray Ionization Mass Spectrometer (LC ESI-MS) at Hiram College. The new LCMS system provides a unique way to elucidate the structure of molecules in complex experiments, and will help faculty at Hiram College to identify fatty acids in biological samples (plasma & insects), detect secondary plant metabolites, analyze large chlorinated compounds, and differentiate metabolic profiles of wild-type and mutant Xenopus. The research projects at Hiram College are at the forefront of their respective fields and will be used as a training ground for undergraduates both in classroom courses and independent research projects. The LCMS will be used as part of a collaborative program at Hiram College, "Research in the Classroom," that allows students to experience real world research problems as part of their coursework. Such an approach fosters independent thought within each student in the classroom as they conduct their research in the field or in the lab. Results from the studies conducted with the LCMS will be broadly disseminated through abstracts and peer reviewed publications, as well as by active participation of students and faculty at professional meetings.