MRI: Acquisition of a Liquid Chromatograph-Mass Spectrometer to Support Multidisciplinary Research and Undergraduate Education at Towson University

凭借主要研究仪器（MRI）和化学研究仪器和设施（CRIF）计划的这一奖项，陶森大学将获得液相色谱-质谱（LC-MS）系统。 该系统将用于分析从各种来源获得的复杂材料的组成，包括来自环境来源，化学反应或生物来源的样品。在该系统中，液相色谱仪（LC）将混合物分离成其单个组分。然后，质谱仪（MS）电离组分，并通过测量离子的质荷比（m/z）来确定其质量。这是一种广泛使用的分析工具，用于确定混合物或材料的成分。该仪器将被学生用于他们的研究，用先进的现代仪器训练他们。实验室课程的学生将接受培训，包括马里兰州唯一的BS法医化学课程的学生。该奖项将用于研究项目，如（a）调查饮用水中所谓的除草剂配方和化学消毒剂之间的惰性成分反应所产生的消毒副产品的形成;（B）分析大气气溶胶的化学成分;（c）改进抗疱疹药物的聚合物控释技术;（d）通过对化学特征进行化学计量分析，提高可可的可追踪性。

With this award from the Major Research Instrumentation (MRI) and Chemistry Research Instrumentation and Facilities (CRIF) programs, Towson University will acquire a liquid chromatography-mass spectrometry (LC-MS) system. The system will be used to analyze the composition of complex materials obtained from various sources including samples from environmental sources, chemical reactions or biological origins. In this system, the liquid chromatograph (LC) separates the mixture into its individual components. Then the mass spectrometer (MS) ionizes the components and determines their mass by measuring the mass to charge ratio (m/z) of the ions. This is a widely used analytical tool to identify what is the composition of a mixture or material. The instrument will be used by students in their research, training them with sophisticated, modern instrumentation. Students in laboratory courses will be trained to use it including students in the only BS Forensic Chemistry program in Maryland.The award will be used in research projects, such as (a) investigating the formation of disinfection by-products in drinking water resulting from reactions between so-called inert constituents of herbicide formulations and chemical disinfectants; (b) analyzing chemical composition of atmospheric aerosols; (c) improving polymer-based controlled-release technology for anti-herpetic drugs; and (d) improving traceability of cocoa through chemometric analysis of chemical signatures.