MRI: Acquisition of a 400 MHz NMR for Undergraduate Research and Research Training

该奖项由主要研究仪器(MRI)和化学研究仪器(CRIF)项目支持。哈维穆德学院的David Vosburg教授及其同事Adam Johnson和Katherine Van Heuvelen购买了一个控制台和探测器，以升级一台400 MHz的核磁共振(核磁共振)光谱仪。总体而言，核磁共振波谱是化学家研究分子结构的最强大的工具之一。它被用来识别未知物质，表征分子中原子的特定排列，并研究分子在溶液或固体中相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱仪是必不可少的。这些核磁共振研究的结果对合成有机/无机化学、材料化学和生物化学都有影响。该仪器是本科生通过独立的学生研究和传统的学术课程进行的教学和研究的组成部分。学生们在这些项目上工作了一整年，特别是在夏季的几个月。该光谱仪也被圣安东尼奥山学院的化学教师和学生以及当地生物科技公司Synedgen的研究人员使用。Synedgen是本科生研究的定期赞助商。授予核磁共振控制台和探测器旨在加强各级研究和教育，特别是在以下领域：(A)仿生合成天然产物，(B)通过自组装制备分子笼，(C)探索催化不对称氢胺化反应，(D)研究生物启发的脱氯反应催化剂，(E)使用依赖敏化剂的注射到用于太阳能电池的氧化锌纳米管光阳极中，(F)表征大气二次有机气溶胶，(G)研究取代的伽马-内酰胺和β-内酰胺的酰胺-缩醛的Claisen重排反应，(H)制备可调的纳米复合气体分离膜和(I)合成天然聚合物衍生物。

This award is supported by the Major Research Instrumentation (MRI) and the Chemistry Research Instrumentation (CRIF) Programs. Professor David Vosburg from Harvey Mudd College and colleagues Adam Johnson and Katherine Van Heuvelen have acquired a console and probes to upgrade a 400 MHz nuclear magnetic resonance (NMR) spectrometer. In general, NMR spectroscopy is one of the most powerful tools available to chemists for the study of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies have an impact in synthetic organic/inorganic chemistry, materials chemistry and biochemistry. This instrument is an integral part of teaching as well as research performed by undergraduate students via independent student research and traditional academic coursework. Students work on these projects year long and especially during the summer months. The spectrometer is also used by chemistry faculty and students at Mount San Antonio College as well as researchers at the local biotech company Synedgen which is a regular sponsor of undergraduate research.The award of an NMR console and probes is aimed at enhancing research and education at all levels, especially in areas such as: (a) synthesizing natural products biomimetically, (b) preparing molecular cages via self-assembly, (c) exploring catalytic asymmetric hydroamination, (d) studying bio-inspired catalysts for dechlorination reactions, (e) using sensitizer-dependent injection into zinc oxide nanotube photoanodes for solar cells, (f) characterizing atmospheric secondary organic aerosols, (g) studying Claisen rearrangements of amide-acetals of substituted gamma- and delta-lactams, (h) preparing tunable nanocomposite gas separation membranes and (i) synthesizing natural polymer derivatives.