2020 Bioinspired Materials GRC/GRS

1.非技术摘要。生物启发材料是指利用生物学的灵感作为指导而设计或组装的材料。生物系统已经开发出组装功能材料的精致方法，以实现传感，分泌，运动和反应等目标。在生物启发材料领域，来自许多不同背景的科学家使用化学，生物化学，材料科学和数学来设计具有生物系统结构的新材料，但可以实现新的目标，如运动或通信。拟议工作的目标是赞助一个会议，作为戈登Reseeacrh生物启发材料会议的一部分。会议将于2020年6月7日至12日在瑞士Les Diablerets举行。相当数量的与会者将是美国研究人员，2/3的与会者是早期研究人员（研究生，博士后助理和早期教授）。戈登研究会议是为期一周的沉浸式体验，其中展示了前沿的未发表的科学，有长时间的问答时间，海报会议，在用餐时讨论科学，以及会议之间的社交活动。这个特别的会议也将有一个戈登研究研讨会，两天前的主要会议，仅研究生和博士后同事介绍他们的工作，和一个电源小时，致力于讨论妇女在科学的主要挑战。总之，会议旨在解决生物启发材料领域的重要思想和概念，由该领域的国际领导人，新一代科学家的重要参与。 2.技术摘要：新兴的跨学科领域的生物启发材料的重点是发展的合成，定向自组装和自然发生的材料的层次组织的基本理解，并使用这种理解来设计新的合成材料，其结构，性能和功能和响应模仿那些天然材料或生命物质。生物启发设计背后的基本概念正越来越多地融入工业、生物、医疗、军事和能源领域的各种材料和设备中，并成为NSF多个项目研究活动的核心焦点。计划的会议包括Protocell工程（主题演讲和早期职业研究者会议），新型膜设计，活性物质和运动性，无膜细胞器，功能性生物启发组装，肽蛋白组装，组织器官和免疫工程。这些都是重要的当前概念，在我们的学科前沿的生物材料。会议将重点讨论生物启发材料设计的基本挑战。该提案将支持37名参与者在戈登生物启发材料研究会议上的注册。GRC的形式和结构旨在让科学家沉浸在生物材料科学的新概念中-重点是突破性的结果和未发表的数据-通过长时间的问答，互动讨论，重要的海报会议和会议之间的社交活动。这个特别的会议也将有一个戈登研究研讨会，两天前的主要会议，仅研究生和博士后同事介绍他们的工作，和电源小时“为提高妇女在科学领域的竞争环境的战略”，致力于对妇女在科学领域的主要挑战进行讨论。对早期研究人员和代表性不足的群体的重视将显著增强本次会议的广泛影响。该奖项反映了NSF的法定使命，并被认为值得通过使用基金会的知识价值和更广泛的影响审查标准进行评估来支持。

1. Non technical abstract.Bioinspired materials are materials that are designed or assembled using the inspiration of biology as a guide. Biological systems have developed exquisite ways of assembling functional materials to achieve goals such as sensing, secretion, motion, and response. In the field of Bioinspired Materials, scientists from many different backgrounds use chemistry, biochemistry, materials science and mathematics to design new materials that have the structure of biological systems, but which can achieve new goals, such as motion or communication.The goal of the proposed work is to sponsor a meeting as part of the Gordon Reseeacrh Conferences on Bioinspired Materials. The meeting will be held in Les Diablerets, Switzerland, June 7-12, 2020. A significant number of the participants will be U.S. researchers, and 2/3 of the meeting partcipants are early stage investigators (graduate students, postdoctoral associates, and early stage professors). Gordon Research Conferences are week-long immersive experiences in which cutting edge, unpublished science is presented, with long question and answer periods, poster sessions, discussion of science over meals, and social engagement between sessions. This particular meeting will also have a Gordon Research Seminar, two days before the main meeting, for solely graduate students and postdoctoral associates to present their work, and a Power Hour, dedicated to discussion the main challenges for women in science. In all, the meeting is designed to address the important ideas and concepts in the field of Bioinspired Materials by international leaders in the field, with significant participation by a new generation of scientists. 2. Technical Abstract.The emerging, interdisciplinary field of Bioinspired Materials focuses on developing a fundamental understanding of the synthesis, directed self-assembly and hierarchical organization of natural occurring materials, and uses this understanding to design new synthetic materials whose structure, properties and function and response mimic those of natural materials or living matter. The fundamental concepts behind bioinspired design are becoming increasingly integrated into a wide range of materials and devices intended for the industrial, biological, medical, military and energy sectors, and represent a core focus of research activity of several programs at NSF. Planned sessions include Protocell Engineering (both a Keynote and an Early Career Investigator session), Novel Membrane Design, Active Matter and Motility, Membraneless Organelles, Functional Bioinspired Assemblies, Peptide & Protein Assembly, Tissues & Organoids, and Immune Engineering. These are important current concepts in biomaterials that are at the forefront of our discipline. The meeting will focus on the fundamental challenges of the design of bioinspired materials.This proposal is to support the registration of 37 participants in the Gordon Research Conference on Bioinspired Materials. The format and structure of the GRC is designed for immersion of scientists into new and emerging concepts in Biomaterials Science – with an emphasis on breaking results and unpublished data - through long question and answer periods, interactive discussion, significant poster sessions and social activities between sessions. This particular meeting will also have a Gordon Research Seminar, two days before the main meeting, for solely graduate students and post-doctoral associates to present their work, and a Power Hour on “Strategies for leveling the playing field for the advancement of women in science,” dedicated to a discussion on the main challenges for women in science. The emphasis on early stage investigators and underrepresented groups will significantly enhance the broader impact of this meeting.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.